甩尾測痛儀主要是用于測量大、小鼠尾巴部受紅外熱刺激的痛覺閾值。實(shí)驗(yàn)時(shí)，當(dāng)動物感覺疼痛，尾巴會輕敲臺面，內(nèi)置傳感器會立刻檢測到，停止計(jì)時(shí)和關(guān)閉光源，即儀器自動記錄反應(yīng)時(shí)間和光源強(qiáng)度。數(shù)據(jù)可通過U盤、USB數(shù)據(jù)線等導(dǎo)出。

甩尾測痛儀中有一可調(diào)強(qiáng)度的紅外光源，其紅外光主要是通過一拋物面反射鏡聚焦在實(shí)驗(yàn)動物的尾巴上。實(shí)驗(yàn)時(shí)，操作人員將實(shí)驗(yàn)動物置于儀器上，把動物的尾巴放在紅外光源處，接受刺激。

特征

• 儀器自動記錄實(shí)驗(yàn)數(shù)據(jù)

• 精度高，避免人為因素引起的誤差

• 包含U盤和軟件

打?。何⑿蜔崦舸蛴C(jī)（需另外購買）
工作溫度：15° - 30° C
開始：紅外開關(guān)
聲級：< 70 dB
紅外強(qiáng)度：10-99級間可調(diào)
反應(yīng)時(shí)間：液晶屏顯示，分辨率為0.1s
校準(zhǔn)：紅外熱輻射計(jì)（需另外購買）
截止時(shí)間：預(yù)置，15 - 60 s間
 
 
文獻(xiàn)

關(guān)于方法
  
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- D.C. Yeomans & H.K. Proudfit: “Characterization of the Foot Withdrawal Response to Noxious Radiant Heat in the Rat”Pain 59: 85-97, 1994.
 
  
涉及疼痛甩尾
 
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-  A. K?ster et alia: “Targeted Disruption of the Orphanin Fq/Nociceptin Gene Increases Stress Susceptibility and Impairs Stress Adaptation In Mice” Neurobiology 96 (18): 10444-10449, 1999
 
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- C.T. Dourish et alia: "The Selective CCK-B Receptor Antagonist L-365,260 Enhances Morphine Analgesia and Prevents Morphine Tolerance in the Rat" Europ. J. Pharmacol. 176: 35-44, 1990
- P.W. Nance & J. Sawinok: "Substance P-Induced Long-Term Blockade of Spinal Adrenergic Analgesia: Reversal by Morphine and Naloxone" J. Pharmacol. Exp. Therap. Vol. 240, No. 3: 972-977,